Opioids exert their effects

Opioids exert their effects primarily through their action on the central nervous system (CNS). They bind to specific receptors in the brain, spinal cord, and other areas of the body, which are known as opioid receptors. There are three main types of opioid receptors: mu, delta, and kappa. When opioids attach to these receptors, they inhibit the transmission of pain signals and alter the perception of pain, leading to analgesia. Additionally, the activation of these receptors can induce feelings of euphoria and relaxation, contributing to their potential for misuse and addiction.